Mitosis in Onion Root Tips - Amrita Vishwa Vidyapeetham In eukaryotes, DNA replication is followed by a process called mitosis which separates the chromosomes in its cell nucleus into two identical sets, in two individual nuclei.. Mitosis is followed by cytokinesis. The process of Mitosis is divided into four stages: Prophase, Metaphase, Anaphase and Telophase.